GABPB1
Sign in to saveAlso known as BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB2, NRF2B1
GA-binding protein subunit beta-1 is a protein that in humans is encoded by the GABPB1 gene.
Gene data
GABPB1- Name
- GA binding protein transcription factor subunit beta 1
- Type
- protein-coding
- Position
- 50,275,389–50,355,440 (−)
- Aliases
- BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB-1, GABPB2, NRF2B1, NRF2B2
- Ensembl
- ENSG00000104064
- RefSeq RNA
- NM_001320910.2, NM_001320915.2, NM_002041.5, NM_005254.6, NM_016654.5
- RefSeq protein
- NP_001307839.1, NP_001307844.1, NP_002032.2, NP_005245.2, NP_057738.1
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
GA binding protein transcription factor subunit beta 1
- Symbol
- GABPB1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:50,275,389-50,355,440
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein GABPB2 PDB 1awc.png
Show 8 more facts
- HomoloGene ID
- 7723
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2553
- genomic end
- 50647605
- genomic start
- 50275389
- chromosome
- human chromosome 15
- cytogenetic location
- 15q21.2
- expressed in
- lactiferous duct
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
GA-binding protein subunit beta-1 is a protein that in humans is encoded by the GABPB1 gene.
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Excerpted from Wikipedia’s “GABPB1” article, available under the CC BY-SA 4.0 licence.