Structure via PubChem · Public domain (PubChem)
gadopiclenol
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Gadopiclenol, sold under the brand name Elucirem or Vueway among others, is a contrast agent used with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and in the body. Gadopiclenol is a paramagnetic macrocyclic non-ionic complex of gadolinium.
Chemical data
- Formula
- C35H54GdN7O15
- Molecular weight
- 970.1 g/mol
- IUPAC name
- 2-[3,9-bis[1-carboxylato-4-(2,3-dihydroxypropylamino)-4-oxobutyl]-3,6,9,15-tetrazabicyclo[9.3.1]pentadeca-1(15),11,13-trien-6-yl]-5-(2,3-dihydroxypropylamino)-5-oxopentanoate;gadolinium(3+)
- SMILES
- C1CN(CC2=NC(=CC=C2)CN(CCN1C(CCC(=O)NCC(CO)O)C(=O)[O-])C(CCC(=O)NCC(CO)O)C(=O)[O-])C(CCC(=O)NCC(CO)O)C(=O)[O-].[Gd+3]
- InChIKey
- GNRQMLROZPOLDG-UHFFFAOYSA-K
- Polar surface area
- 352 Ų
- H-bond donors
- 9
- H-bond acceptors
- 19
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 970.291892928
Show 4 more facts
- subject has role
- contrast agent
- canonical SMILES
- O=C(O)C(CCC([O-])=NCC(O)CO)N1CCN(C(CCC([O-])=NCC(O)CO)C(=O)O)Cc2cccc(n2)CN(C(CCC([O-])=NCC(O)CO)C(=O)O)CC1.[Gd+3]
- chemical formula
- C₃₅H₅₄GdN₇O₁₅
- legal status (medicine)
- boxed warning
Sources (1)
via Wikidata · CC0
~3 min read
Encyclopedic overview
7 sectionsContents
- Pharmacology
- Safety
- Society and culture
- European Union
- Brand names
- References
- External links
Gadopiclenol, sold under the brand name Elucirem or Vueway among others, is a contrast agent used with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and in the body. Gadopiclenol is a paramagnetic macrocyclic non-ionic complex of gadolinium.
Gadopiclenol was approved for medical use in the United States in September 2022, and in the European Union in December 2023. Developed initially by Guerbet with intellectual property contributions from Bracco Imaging, gadopiclenol was commercialized following a strategic collaboration between the companies for manufacturing, research, and distribution.
Excerpted from Wikipedia’s “gadopiclenol” article, available under the CC BY-SA 4.0 licence.