GBP5
Sign in to saveAlso known as GBP-5, guanylate binding protein 5
Guanylate binding protein 5 is a protein in humans that is encoded by the GBP5 gene.
Gene data
GBP5- Name
- guanylate binding protein 5
- Type
- protein-coding
- Position
- 89,256,189–89,272,892 (−)
- Aliases
- GBP-5
- Ensembl
- ENSG00000154451
- RefSeq RNA
- NM_001134486.4, NM_001391920.1, NM_052942.5
- RefSeq protein
- NP_001127958.1, NP_001378849.1, NP_443174.1
This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
guanylate binding protein 5
- Symbol
- GBP5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:89,256,189-89,272,892
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 14183
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/115362
- genomic end
- 89272860
- genomic start
- 89256189
- chromosome
- human chromosome 1
- cytogenetic location
- 1p22.2
- expressed in
- testicle
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Guanylate binding protein 5 is a protein in humans that is encoded by the GBP5 gene.
== See also == Guanylate, conjugate base of guanosine monophosphate Guanylate-binding protein
Excerpted from Wikipedia’s “GBP5” article, available under the CC BY-SA 4.0 licence.