ginsenoside
Sign in to saveAlso known as ginsenosides, panaxoside, panaxosides
thumb|The chemical structure of the ginsenoside Rg1, a member of the dammarane family of molecules. Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively in the plant genus Panax (ginseng), which has a long history of use in traditional medicine that has led to the study of pharmacological effects of ginseng compounds. As a class, ginsenosides exhibit a large variety of subtle and difficult-to-characterize biological effects when studied in isolation.
Research
9,596 papers- Ginsenoside Rg1: A Neuroprotective Natural Dammarane-Type Triterpenoid Saponin With Anti-Depressive Properties.CNS neuroscience & therapeutics · 2024
- Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential Therapeutic Applications.Current topics in medicinal chemistry · 2024
- Ginsenoside Rb1 and mitochondria: A short review of the literature.Molecular and cellular probes · 2019
- Pharmacological mechanisms and drug delivery systems of ginsenoside Rg3: A comprehensive review.Pharmacological research · 2025
- Anti-Angiogenic Properties of Ginsenoside Rg3.Molecules (Basel, Switzerland) · 2020
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Article
10 sectionsContents
- Nomenclature
- Classification and structure
- Biosynthesis
- Function for the plant
- Chemical reactions
- Metabolism
- Biological effects
- Sources
- See also
- References
thumb|The chemical structure of the ginsenoside Rg1, a member of the dammarane family of molecules. Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively in the plant genus Panax (ginseng), which has a long history of use in traditional medicine that has led to the study of pharmacological effects of ginseng compounds. As a class, ginsenosides exhibit a large variety of subtle and difficult-to-characterize biological effects when studied in isolation.
Ginsenosides can be isolated from various parts of the plant, though typically from the roots, and can be purified by column chromatography. The chemical profiles of Panax species are distinct; although Asian ginseng, Panax ginseng, has been most widely studied due to its use in traditional Chinese medicine, there are ginsenosides unique to American ginseng (Panax quinquefolius) and Japanese ginseng (Panax japonicus). Ginsenoside content also varies significantly due to environmental effects. The leaves and stems have emerged as a more abundant and easier-to-extract source of ginsenosides. Ginsenosides have also been found in jiaogulan, making jiaogulan the first plant outside of Araliaceae to contain ginsenosides.