GPD1L
Sign in to saveAlso known as GPD1-L, glycerol-3-phosphate dehydrogenase 1-like, glycerol-3-phosphate dehydrogenase 1 like
GPD1L is a human gene. The protein encoded by this gene contains a glycerol-3-phosphate dehydrogenase (NAD+) motif and shares 72% sequence identity with GPD1.
Gene data
GPD1L- Name
- glycerol-3-phosphate dehydrogenase 1 like
- Type
- protein-coding
- Aliases
- GPD1-L
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010].
via MyGene.info
Gene · Ensembl
glycerol-3-phosphate dehydrogenase 1 like
- Symbol
- GPD1L
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:32,105,689-32,168,715
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 56097
- exact match
- identifiers.org/ncbigene/23171
- genomic end
- 32168709
- genomic start
- 32147181
- chromosome
- human chromosome 3
- cytogenetic location
- 3p22.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
6 sectionsContents
- Structure
- Tissue distribution
- Disease linkage
- See also
- References
- External links
GPD1L is a human gene. The protein encoded by this gene contains a glycerol-3-phosphate dehydrogenase (NAD+) motif and shares 72% sequence identity with GPD1.
==Structure== GPD1L contains the following domains: N-terminal – NAD+ consensus binding site a site homologous to the cardiac sodium channel SCN5A C-terminal lysine-206 residue
Excerpted from Wikipedia’s “GPD1L” article, available under the CC BY-SA 4.0 licence.