H2AZ1

Name

H2A.Z variant histone 1

Type

protein-coding

Position

99,948,051–99,950,540 (−)

Aliases

H2A.Z-1, H2A.z, H2A/z, H2AFZ, H2AZ

Ensembl

ENSG00000164032

RefSeq RNA

NM_002106.4

RefSeq protein

NP_002097.1

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

H2A.Z variant histone 1

Symbol

H2AZ1

Biotype

Protein coding

Organism

Homo sapiens

Location

4:99,948,051-99,950,540

Strand

Reverse (−)

Assembly

GRCh38