HTRA2

Also known as AI481710, Omi, Prss25, mnd2, PARK13, HtrA serine peptidase 2, MGCA8

protein-coding gene in the species Homo sapiens

Gene data

HTRA2

Name: HtrA serine peptidase 2
Type: protein-coding
Aliases: MGCA8, OMI, PARK13, PRSS25

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016].

via MyGene.info