File:Hyperplasia_vs_Hypertrophy.svg · Wikimedia Commons · See Wikimedia Commons
hyperplasia
Sign in to saveAlso known as Hyperplastic, hypergenesis
Hyperplasia (from ancient Greek ὑπέρ huper 'over' + πλάσις plasis 'formation'), or hypergenesis, is an enlargement of an organ or tissue caused by an increase in the amount of organic tissue that results from cell proliferation. It may lead to the gross enlargement of an organ, and the term is sometimes confused with benign neoplasia or benign tumor.
Key facts
- Medical condition (new).name
- Hyperplasia
- Medical condition (new).image
- Hyperplasia vs Hypertrophy.svg
- Medical condition (new).caption
- Whereas hypertrophy stems from an increase in cell size, hyperplasia results from an increase in cell number.
- Medical condition (new).field
- Pathology
- Medical condition (new).types
- Benign prostatic hyperplasia, Hyperplasia of the breast(many more)
- Medical condition (new).diagnosis
- Biopsy
- Medical condition (new).treatment
- Depends which type (see types)
via Wikipedia infobox
Research
144,567 papers- Hyperplasia in glands with hormone excess.Endocrine-related cancer · 2016
- [Thymic hyperplasia: A study of 46 cases].Annales de pathologie · 2021
- Florid follicular lymphoid hyperplasia of the palate: review of the literature and report of an illustrative case.Quintessence international (Berlin, Germany : 1985) · 2024
- Pediatric follicular lymphomas, marginal zone lymphomas, and marginal zone hyperplasia.American journal of clinical pathology · 2004
- [Adrenocortical tumours].Der Pathologe · 2003
via PubMed
Clinical Trials
1,273 registered- NACOMPLETEDPivotal Study to Assess the Safety and Effectiveness of the iTind DeviceMedi-Tate Ltd. · NCT02506465
- RECRUITINGProtocollo N 2014 - Benign Prostatic HyperplasiaIRCCS San Raffaele · NCT06182189
- COMPLETEDAn Observational Study of Radial Access Embolization Procedures Using HydroPearl MicrospheresTerumo Medical Corporation · NCT04272216
- NANOT_YET_RECRUITINGHigh Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet ObstructionIcahn School of Medicine at Mount Sinai · NCT07194187
- NACOMPLETEDProspective Randomized Controlled Trial Comparing Water and Air Colonoscopy in a Community Based SettingUniversity of California, Davis · NCT01729416
- PHASE2COMPLETEDStudy of Efficacy and Safety of Osilodrostat in Cushing's SyndromeNovartis Pharmaceuticals · NCT02468193
Wikidata facts
- Image
- Hyperplasia vs Hypertrophy.svg
Show 2 more facts
- Commons category
- Hyperplasia
- NCI Thesaurus ID
- C3113
Sources (6)
via Wikidata · CC0
~6 min read
Article
8 sectionsContents
- Causes
- Mechanism
- Role in disease
- Types
- See also
- References
- Further reading
- External links
Hyperplasia (from ancient Greek ὑπέρ huper 'over' + πλάσις plasis 'formation'), or hypergenesis, is an enlargement of an organ or tissue caused by an increase in the amount of organic tissue that results from cell proliferation. It may lead to the gross enlargement of an organ, and the term is sometimes confused with benign neoplasia or benign tumor.
Hyperplasia is a common preneoplastic response to stimulus. Microscopically, cells resemble normal cells but are increased in numbers. Sometimes cells may also be increased in size (hypertrophy). Hyperplasia is different from hypertrophy in that the adaptive cell change in hypertrophy is an increase in the size of cells, whereas hyperplasia involves an increase in the number of cells.