ilomastat

Also known as GM6001

Ilomastat (INN; development code GM6001; proprietary name Galardin) is a broad-spectrum matrix metalloproteinase inhibitor.

In the Vinony graph

Within Vinony's link graph, ilomastat is referenced by 4 other articles, and connects out to zinc, digital object identifier and chemical formula.

It is catalogued under topics including Hydroxamic acids, Isobutyl compounds and Matrix metalloproteinase inhibitors.

Its subject is documented across 5 Wikipedia language editions.

Chemical data

Formula: C20H28N4O4
Molecular weight: 388.5 g/mol
IUPAC name: (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamide
SMILES: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC
InChIKey: NITYDPDXAAFEIT-DYVFJYSZSA-N
XLogP: 0.9
Polar surface area: 123 Å²
H-bond donors: 5
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Mass: 388.211055376

Show 4 more facts

chemical formula: C₂₀H₂₈N₄O₄
isomeric SMILES: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC
Commons category: Ilomastat
canonical SMILES: CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(=O)NO)CC(C)C

Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections

Contents

References

{{Chembox | Name = GM6001 | ImageFile = Ilomastat.svg | ImageClass = skin-invert-image | ImageSize = | PIN = (3R)-N1-Hydroxy-N4-{(1S)-1-[(1H-indol-3-yl)methyl]-2-(methylamino)-2-oxoethyl}-3-(2-methylpropyl)butanediamide | OtherNames = Galardin, GM6001

| Section1 =

Excerpted from Wikipedia’s “ilomastat” article, available under the CC BY-SA 4.0 licence.