iohexol

Also known as Exypaque, Omnipaque 350, Omnipaque 140, Omnipaque, Omnipaque 300, Omnipaque 180, WIN-39424, Omnipaque 240

Iohexol, sold under the trade names Omnipaque and Iodaque among others, is a contrast agent used for X-ray imaging. This includes when visualizing arteries, veins, ventricles of the brain, the urinary system, and joints, as well as during computed tomography (CT scan). It is given by mouth, injection into a vein, or into a body cavity.

Key facts

Drug.Verifiedfields: changed
Drug.verifiedrevid: 461935422
Drug.image: Iohexol.svg
Drug.image_class: skin-invert-image
Drug.tradename: Iodaque, Hexopaque, Oraltag, others
Drug.DailyMedID: Iohexol
Drug.routes_of_administration: Intrathecal, intravascular, by mouth, intracavital, rectal
Drug.ATC_prefix: V08
Drug.ATC_suffix: AB02
Drug.legal_CA: Rx-only
Drug.legal_US: Rx-only
Drug.legal_status: Rx-only
Drug.protein_bound: Low
Drug.metabolism: Nil
Drug.elimination_half life: Variable
Drug.excretion: Kidney, unchanged
Drug.CAS_number: 66108-95-0
Drug.PubChem: 3730

via Wikipedia infobox

Research

6,578 papers

Is Iohexol a Possible Method for Estimating Glomerular Filtration Rate?Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia · 2025
Toxicology of iohexol.Investigative radiology · 1985
Assessment of Iohexol Serum Clearance by LC-MS/MS with Isotopically Labeled Internal Standard.Methods in molecular biology (Clifton, N.J.) · 2024
Iohexol is an intestinal permeability marker in broilers under coccidiosis challenge.Poultry science · 2023
Iohexol.Acta radiologica. Supplementum · 1980

via PubMed

Wikidata facts

Mass: 820.880323

Show 4 more facts

chemical formula: C₁₉H₂₆I₃N₃O₉
canonical SMILES: CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
World Health Organisation international non-proprietary name: iohexol
Commons category: Iohexol

Sources (4)

via Wikidata · CC0

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Article

6 sections

Contents

Chemistry
Adverse effects
Society and culture
Naming
Available forms
References

Side effects include vomiting, skin flushing, headache, itchiness, kidney problems, and low blood pressure. Less commonly allergic reactions or seizures may occur. Allergies to povidone-iodine or shellfish do not affect the risk of side effects more than other allergies. Use in the later part of pregnancy may cause hypothyroidism in the baby. Iohexol is an iodinated non-ionic radiocontrast agent. It is in the low osmolar family.