Structure via PubChem · Public domain (PubChem)
isoflurophate
Sign in to saveAlso known as Floropryl, Isopropyl Phosphorofluoridate, Diisopropyl Fluorophosphonate, Diisopropylfluorophosphoric acid ester, Diisopropyl fluorophosphate, Diisopropylphosphorofluoridate, Diisopropoxyphosphoryl Fluoride, Fluorodiisopropyl Phosphate
chemical compound
Chemical data
- Formula
- C6H14FO3P
- Molecular weight
- 184.15 g/mol
- IUPAC name
- 2-[fluoro(propan-2-yloxy)phosphoryl]oxypropane
- SMILES
- CC(C)OP(=O)(OC(C)C)F
- InChIKey
- MUCZHBLJLSDCSD-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 35.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1957
- Admin. routes
- topical
- Indications
- glaucoma
via ChEMBL · EBI
Research
3,361 papers- Isoflurophate versus glasses in evaluating the accommodative element in esotropia.Archives of ophthalmology (Chicago, Ill. : 1960) · 1966
- ISOFLUROPHATE (DFP) IN THE HANDLING OF ESOTROPIA.Archives of ophthalmology (Chicago, Ill. : 1960) · 1964
- Regional differences in brain-soluble acetylcholinesterase and its molecular forms after acute poisoning by isoflurophate in rats.Clinical toxicology · 1981
- Gradual increase in the sensitivity of extraocular muscles to acetylcholine during topical treatment of rabbit eyes with isoflurophate.American journal of ophthalmology · 1981
- USE OF isoflurophate in strabismus.Journal of the American Medical Association · 1957
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 184.066459
- Has use
- medication
Show 8 more facts
- chemical formula
- C₆H₁₄FO₃P
- World Health Organisation international non-proprietary name
- fluostigmine
- medical condition treated
- glaucoma
- different from
- VESA Digital Flat Panel
- canonical SMILES
- CC(C)OP(=O)(OC(C)C)F
- Commons category
- Diisopropyl fluorophosphate
- melting point
- -82
- subject has role
- protease inhibitor
Sources (6)
via Wikidata · CC0