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لووفن اسیل مورفان

Structure via PubChem · Public domain (PubChem)

EntityQ6535821· pop 8· linked from 15 articles

لووفن اسیل مورفان

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Levophenacylmorphan is a morphinan derivative that acts as an opioid agonist. It has potent analgesic effects and is around 10x more potent than morphine. Adverse effects associated with its use are those of the opioids as a whole, including pruritus, nausea, respiratory depression, euphoria and development of tolerance and dependence to its effects.

Chemical data

Formula
C24H27NO2
Molecular weight
361.5 g/mol
IUPAC name
2-[(1R,9R,10R)-4-hydroxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-17-yl]-1-phenylethanone
SMILES
C1CC[C@@]23CCN([C@@H]([C@@H]2C1)CC4=C3C=C(C=C4)O)CC(=O)C5=CC=CC=C5
InChIKey
RCYBMSQOSGJZLO-BGWNEDDSSA-N
XLogP
4.2
Polar surface area
40.5 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
361.204
Show 3 more facts
chemical formula
C₂₄H₂₇NO₂
canonical SMILES
C1CCC23CCN(C(C2C1)CC4=C3C=C(C=C4)O)CC(=O)C5=CC=CC=C5
isomeric SMILES
C1CC[C@@]23CCN([C@@H]([C@@H]2C1)CC4=C3C=C(C=C4)O)CC(=O)C5=CC=CC=C5
Sources (2)

via Wikidata · CC0

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via Wikidata sitelinks · CC0