lupeol

Also known as fagarasterol, monogynol B, beta-viscol, (3-beta)-Lup-20(29)-en-3-ol, Faganasterol, Clerodol

Lupeol is a pharmacologically active pentacyclic triterpenoid. It has several potential medicinal properties, like anticancer and anti-inflammatory activity.

Research

1,647 papers

Lupeol protects against cardiac hypertrophy via TLR4-PI3K-Akt-NF-κB pathways.Acta pharmacologica Sinica · 2022
Lupeol: A dietary and medicinal triterpene with therapeutic potential.Biochemical pharmacology · 2024
Lupeol alleviates autoimmune myocarditis by suppressing macrophage pyroptosis and polarization via PPARα/LACC1/NF-κB signaling pathway.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2024
Lupeol and its derivatives as anticancer and anti-inflammatory agents: Molecular mechanisms and therapeutic efficacy.Pharmacological research · 2021
Lupeol and Its Role in Chronic Diseases.Advances in experimental medicine and biology · 2016

via PubMed

Wikidata facts

Mass: 426.386166

Show 4 more facts

chemical formula: C₃₀H₅₀O
isomeric SMILES: CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)C
canonical SMILES: CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C
Commons category: Lupeol

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Article

6 sections

Contents

Natural occurrences
Total synthesis
Biosynthesis
Pharmacology
See also
References

Lupeol is a pharmacologically active pentacyclic triterpenoid. It has several potential medicinal properties, like anticancer and anti-inflammatory activity.

== Natural occurrences == Lupeol is found in a variety of plants, including mango, Acacia visco and Abronia villosa. It is also found in dandelion coffee. Lupeol is present as a major component in Camellia japonica leaf.