magaldrate

Also known as Magaldrato, Magaldratum, Aluminum magnesium hydroxide hydrate

Magaldrate (INN) is a common antacid drug that is used for the treatment of duodenal and gastric ulcers, esophagitis from gastroesophageal reflux.

Chemical data

Formula: AlHMgO5S+2
Molecular weight: 164.36 g/mol
IUPAC name: aluminum;magnesium;hydroxide;sulfate
SMILES: [OH-].[O-]S(=O)(=O)[O-].[Mg+2].[Al+3]
InChIKey: JIFPTBLGXRKRAO-UHFFFAOYSA-K
Polar surface area: 89.6 Å²
H-bond donors: 1
H-bond acceptors: 5
Formal charge: 2

via PubChem

Research

89 papers

Magaldrate and almasilate--complex buffering antacids.Drug and therapeutics bulletin · 1985
Evaluation of Aluminum and Magnesium Absorption Following the Oral Administration of an Antacid Suspension Containing Magaldrate in Healthy Women Under Fed Conditions.Advances in therapy · 2024
[A layered lattice antacid with long-term effectiveness. Profile of action and safety exemplified by magaldrate].Fortschritte der Medizin · 1993
Magaldrate stimulates endogenous prostaglandin E2 synthesis in human gastric mucosa in vitro and in vivo.Hepato-gastroenterology · 1998
Cytoprotective and antiulcer activities of the antacid magaldrate in the rat.Arzneimittel-Forschung · 1989

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 163.91995230218004
Has use: medication

Show 4 more facts

medical condition treated: hiatus hernia
canonical SMILES: [OH-].[O-]S(=O)(=O)[O-].[Mg+2].[Al+3]
chemical formula: HAlMgO₅S²⁺
subject has role: antacid

Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

5 sections

Contents

Development
Available forms
Pharmacology
Interactions and adverse reactions
References

{{Drugbox | Watchedfields = changed | verifiedrevid = 455253688 | IUPAC_name = Magnesium aluminate monohydrate | image = [Al^{3+}][Mg^{2+}]2[HO^{-}]7[H2O]

Excerpted from Wikipedia’s “magaldrate” article, available under the CC BY-SA 4.0 licence.

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