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GeneQ18034740· pop 5· linked from 7 articles

Also known as ACVRIP1, AIP-1, AIP1, ARIP1, MAGI-2, SSCAM, membrane associated guanylate kinase, WW and PDZ domain containing 2, NPHS15

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 also known as membrane-associated guanylate kinase inverted 2 (MAGI-2) and atrophin-1-interacting protein 1 (AIP-1) is an enzyme that in humans is encoded by the MAGI2 gene.

Gene data

MAGI2
Name
membrane associated guanylate kinase, WW and PDZ domain containing 2
Type
protein-coding
Aliases
ACVRIP1, AIP-1, AIP1, ARIP1, MAGI-2, NPHS15, SSCAM

The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

membrane associated guanylate kinase, WW and PDZ domain containing 2

Symbol
MAGI2
Biotype
Protein coding
Organism
Homo sapiens
Location
7:78,017,055-79,453,845
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein MAGI2 PDB 1uep.png
Show 5 more facts
HomoloGene ID
8189
cytogenetic location
7q21.11
genomic end
79453667
genomic start
78017055
Sources (3)

via Wikidata · CC0

~1 min read

Article

4 sections
Contents
  • Function
  • Interactions
  • References
  • Further reading

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 also known as membrane-associated guanylate kinase inverted 2 (MAGI-2) and atrophin-1-interacting protein 1 (AIP-1) is an enzyme that in humans is encoded by the MAGI2 gene.

== Function ==

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