mastocytosis
Sign in to saveAlso known as mast cell hyperplasia
Mastocytosis, a type of mast cell disease, is a rare disorder affecting both children and adults caused by the accumulation of functionally defective mast cells (also called mastocytes) and CD34+ mast cell precursors.
Key facts
- Medical condition (new).name
- Mastocytosis
- Medical condition (new).image
- Mastocytosis - cropped - very high mag.jpg
- Medical condition (new).caption
- Micrograph of mastocytosis. Skin biopsy. H&E stain.
- Medical condition (new).field
- Clinical Immunology and Allergy, Oncology, hematology
- Medical condition (new).synonyms
- Clonal bone marrow disorder
via Wikipedia infobox
Research
8,859 papers- Cutaneous mastocytosis: A dermatological perspective.The Australasian journal of dermatology · 2021
- Mastocytosis demystified.Hematology. American Society of Hematology. Education Program · 2023
- The international consensus classification of mastocytosis and related entities.Virchows Archiv : an international journal of pathology · 2023
- Mast Cells, Mastocytosis, and Related Disorders.The New England journal of medicine · 2015
- [Mastocytosis in children].Dermatologie (Heidelberg, Germany) · 2023
via PubMed
Wikidata facts
- Subclass of
- disease
- Image
- Mastocytosis - cropped - very high mag.jpg
Show 6 more facts
- NCI Thesaurus ID
- C84269
- health specialty
- oncology
- Commons category
- Mastocytosis
- exact match
- purl.obolibrary.org/obo/HP_0100495
- drug or therapy used for treatment
- cromoglicic acid
- on focus list of Wikimedia project
- WikiProject Medicine
Sources (2)
via Wikidata · CC0
~12 min read
Encyclopedic overview
20 sectionsContents
- Signs and symptoms
- Pathophysiology
- Diagnosis
- Major criterion
- Minor criteria
- Other mast cell diseases
- Classification
- Cutaneous mastocytosis (CM)
- Systemic mastocytosis (SM)
- Treatment
- Anti-mediator therapy
- Cytoreductive therapy
- Other
- Prognosis
- Epidemiology
- Research
- History
- See also
- References
- Further reading
Mastocytosis, a type of mast cell disease, is a rare disorder affecting both children and adults caused by the accumulation of functionally defective mast cells (also called mastocytes) and CD34+ mast cell precursors.
People affected by mastocytosis are susceptible to a variety of symptoms, including itching, hives, and anaphylactic shock, caused by the release of histamine and other pro-inflammatory substances from mast cells.
Excerpted from Wikipedia’s “mastocytosis” article, available under the CC BY-SA 4.0 licence.