polycythemia vera
Sign in to saveAlso known as Osler-Vaquez syndrome, PV, erythremia (morphologic abnormality), polycythaemia rubra vera, proliferative polycythaemia, Polycythemia Rubra Vera, POLYCYTHEMIA VERA; PV, Vaquez disease
human disease
Key facts
- Other names
- Polycythaemia vera (PV, PCV), erythremia, primary polycythemia, Vaquez disease, Osler-Vaquez disease, polycythemia rubra vera
- Specialty
- Oncology , hematology
via Wikipedia infobox
Research
9,770 papers- [Polycythemia vera].Folia haematologica (Leipzig, Germany : 1928) · 1970
- Polycythaemia vera.Nature reviews. Disease primers · 2025
- [Unusual progression of polycythemia vera].Innere Medizin (Heidelberg, Germany) · 2024
- [Polycythemia vera].Belgisch tijdschrift voor geneeskunde · 1954
- [Polycythemia vera].Praxis · 2012
via PubMed
Wikidata facts
- Subclass of
- disease
- Image
- Polycythemia vera, blood smear.jpg
Show 9 more facts
- NCI Thesaurus ID
- C3336
- health specialty
- hematology
- drug or therapy used for treatment
- pipobroman
- exact match
- purl.obolibrary.org/obo/DOID_8997
- Commons category
- Polycythemia vera
- ICD-9-CM
- 238.4
- genetic association
- JAK2
- on focus list of Wikimedia project
- WikiProject Medicine
- nickname
- Էրիթրեմիա
via Wikidata · CC0
~8 min read
Encyclopedic overview
In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. Approximately 98% of PV patients have a JAK2 gene mutation in their blood-forming cells (compared with 0.1-0.2% of the general population).
Most of the health concerns associated with PV, such as thrombosis, are caused by the blood being thicker as a result of the increased red blood cells.
Excerpted from Wikipedia’s “polycythemia vera” article, available under the CC BY-SA 4.0 licence.