polycythemia vera

Also known as Osler-Vaquez syndrome, PV, erythremia (morphologic abnormality), polycythaemia rubra vera, proliferative polycythaemia, Polycythemia Rubra Vera, POLYCYTHEMIA VERA; PV

Key facts

Other names: Polycythaemia vera (PV, PCV), erythremia, primary polycythemia, Vaquez disease, Osler-Vaquez disease, polycythemia rubra vera
Specialty: Oncology , hematology

via Wikipedia infobox

Research

9,770 papers

[Polycythemia vera].Folia haematologica (Leipzig, Germany : 1928) · 1970
Polycythaemia vera.Nature reviews. Disease primers · 2025
[Unusual progression of polycythemia vera].Innere Medizin (Heidelberg, Germany) · 2024
[Polycythemia vera].Belgisch tijdschrift voor geneeskunde · 1954
[Polycythemia vera].Praxis · 2012

via PubMed

~8 min read

Article

In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. Approximately 98% of PV patients have a JAK2 gene mutation in their blood-forming cells (compared with 0.1-0.2% of the general population).

Most of the health concerns associated with PV, such as thrombosis, are caused by the blood being thicker as a result of the increased red blood cells.