Structure via PubChem · Public domain (PubChem)
pipobroman
Sign in to saveAlso known as A-8103, Vercyte®, Vercyte
Pipobroman (trade names Vercite, Vercyte) is an anti-cancer drug that probably acts as an alkylating agent, and is marketed in France and Italy.
In the Vinony graph
Vinony's link graph records 278 inbound references to pipobroman, and connects out to tiazofurin, medication and digital object identifier.
It is catalogued under topics including Alkylating antineoplastic agents, Carboxamides and Drugs with no legal status.
Vinony links it to 9 Wikipedia language editions.
Chemical data
- Formula
- C10H16Br2N2O2
- Molecular weight
- 356.05 g/mol
- IUPAC name
- 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one
- SMILES
- C1CN(CCN1C(=O)CCBr)C(=O)CCBr
- InChIKey
- NJBFOOCLYDNZJN-UHFFFAOYSA-N
- XLogP
- 0.4
- Polar surface area
- 40.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1966
- Admin. routes
- oral
- Indications
- polycythemia vera, neoplasm
via ChEMBL · EBI
Research
118 papers- Treatment of polycythemia vera and essential thrombocythemia: the role of pipobroman.Leukemia & lymphoma · 2003
- Bone marrow aplasia after pipobroman: an immune-mediated mechanism?British journal of haematology · 2001
- Long-term incidence of hematological evolution in three French prospective studies of hydroxyurea and pipobroman in polycythemia vera and essential thrombocythemia.Seminars in thrombosis and hemostasis · 2006
- Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study.Leukemia · 2013
- Polycythemia vera.Internal and emergency medicine · 2010
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 353.957851952
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₀H₁₆Br₂N₂O₂
- medical condition treated
- chronic myeloid leukemia
- canonical SMILES
- C1CN(CCN1C(=O)CCBr)C(=O)CCBr
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Pipobroman (trade names Vercite, Vercyte) is an anti-cancer drug that probably acts as an alkylating agent, and is marketed in France and Italy.
== References ==
Excerpted from Wikipedia’s “pipobroman” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
via Wikidata sitelinks · CC0