belzutifan

Also known as 3-{[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Welireg

Belzutifan, sold under the brand name Welireg, is an anti-cancer medication used for the treatment of von Hippel–Lindau disease-associated renal cell carcinoma. It is taken by mouth. Belzutifan is an hypoxia-inducible factor-2 alpha (HIF-2α) inhibitor.

In the Vinony graph

Vinony's link graph records 277 inbound references to belzutifan, and connects out to chemotherapy, tiazofurin and public domain.

It is catalogued under topics including Benzonitriles, Diphenyl ethers and Drugs with non-standard legal status.

Vinony links it to 10 Wikipedia language editions.

Key facts

Drug.MedlinePlus: a621047
Drug.DailyMedID: Belzutifan
Drug.pregnancy_AU: D
Drug.image: Belzutifan.svg
Drug.image_class: skin-invert-image
Drug.tradename: Welireg
Drug.routes_of_administration: By mouth
Drug.class: Antineoplastic
Drug.ATC_prefix: L01
Drug.ATC_suffix: XX74
Drug.legal_AU: S4
Drug.legal_CA: Rx-only
Drug.legal_UK: POM
Drug.legal_US: Rx-only
Drug.legal_EU: Rx-only
Drug.CAS_number: 1672668-24-4
Drug.PubChem: 117947097
Drug.DrugBank: DB15463

via Wikipedia infobox

Chemical data

Formula: C17H12F3NO4S
Molecular weight: 383.3 g/mol
IUPAC name: 3-[[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl]oxy]-5-fluorobenzonitrile

via PubChem

Wikidata facts

Subclass of: chemical compound
Mass: 383.044

Show 6 more facts

isomeric SMILES: CS(=O)(=O)C1=C2[C@@H]([C@@H]([C@@H](C2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)F)F)O
chemical formula: C₁₇H₁₂F₃NO₄S
canonical SMILES: CS(=O)(=O)C1=C2C(C(C(C2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)F)F)O
medical condition treated: von Hippel-Lindau disease
Commons category: Belzutifan
legal status (medicine): boxed warning

Sources (4)

via Wikidata · CC0

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