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vericiguat

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EntityQ27283201· pop 11· linked from 166 articles

vericiguat

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Vericiguat, sold under the brand name Verquvo, is a medication used to reduce the risk of cardiovascular death and hospitalization in certain patients with heart failure after a recent acute decompensation event. It is taken by mouth. Vericiguat is a soluble guanylate cyclase (sGC) stimulator.

Key facts

Drug.image
Vericiguat Structural formula V1.svg
Drug.image_class
skin-invert-image
Drug.tradename
Verquvo
Drug.DailyMedID
Vericiguat
Drug.pregnancy_AU
D
Drug.pregnancy_category
Contraindicated
Drug.routes_of_administration
By mouth
Drug.class
Soluble guanylate cyclase activator
Drug.ATC_prefix
C01
Drug.ATC_suffix
DX22
Drug.legal_AU
S4
Drug.legal_CA
Rx-only
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only
Drug.CAS_number
1350653-20-1
Drug.PubChem
54674461
Drug.DrugBank
DB15456
Drug.ChemSpiderID
32700337

via Wikipedia infobox

Chemical data

Formula
C19H16F2N8O2
Molecular weight
426.4 g/mol
IUPAC name
methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate

via PubChem

~5 min read

Encyclopedic overview

10 sections
Contents
  • Medical uses
  • Adverse effects
  • Pharmacology
  • Pharmacokinetics
  • History
  • Society and culture
  • Legal status
  • References
  • Further reading
  • External links

Vericiguat, sold under the brand name Verquvo, is a medication used to reduce the risk of cardiovascular death and hospitalization in certain patients with heart failure after a recent acute decompensation event. It is taken by mouth. Vericiguat is a soluble guanylate cyclase (sGC) stimulator.

Common side effects include low blood pressure and low red cell count (anemia).

Excerpted from Wikipedia’s “vericiguat” article, available under the CC BY-SA 4.0 licence.