oxyfedrine
Sign in to saveAlso known as 3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)propan-1-one
Oxyfedrine, sold under the brand names Ildamen and Myofedrin among others, is a sympathomimetic agent and coronary vasodilator which is used in the treatment of coronary heart disease, angina pectoris, and acute myocardial infarction. It is taken by mouth or intravenously.
Research
216 papers- Oxyfedrine.Lancet (London, England) · 1981
- Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy.Cancer science · 2020
- Metabolism of oxyfedrine.Naunyn-Schmiedeberg's archives of pharmacology · 1972
- Effects of oxyfedrine on isolated portal vein and other smooth muscles.British journal of pharmacology · 1973
- Effect of intravenous oxyfedrine on exercise in patients with ischaemic heart disease.Indian heart journal · 1991
via PubMed
Wikidata facts
- Mass
- 313.167794
Show 5 more facts
- chemical formula
- C₁₉H₂₃NO₃
- canonical SMILES
- CC(C(C1=CC=CC=C1)O)NCCC(=O)C2=CC(=CC=C2)OC
- isomeric SMILES
- C[C@@H]([C@@H](C1=CC=CC=C1)O)NCCC(=O)C2=CC(=CC=C2)OC
- Commons category
- Oxyfedrine
- defined daily dose
- 40
Sources (3)
via Wikidata · CC0
~3 min read
Article
7 sectionsContents
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Synthesis
- Research
- References
Oxyfedrine, sold under the brand names Ildamen and Myofedrin among others, is a sympathomimetic agent and coronary vasodilator which is used in the treatment of coronary heart disease, angina pectoris, and acute myocardial infarction. It is taken by mouth or intravenously.
The drug acts as a β-adrenergic receptor partial agonist. It may also act as a norepinephrine releasing agent via its major active metabolite norephedrine. Oxyfedrine is a phenethylamine and amphetamine derivative.