desloratadine
Also known as SCH-34117, descarboethoxyloratadine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Desloratadine, sold under the brand name Aerius among others, is a tricyclic H1 inverse agonist that is used to treat allergies. It is the major active metabolite of loratadine.
Key facts
- Drug.verifiedrevid
- 460777963
- Drug.image
- Desloratadine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 222
- Drug.image2
- Desloratadine 3D ball-and-stick.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Aerius, others
- Drug.MedlinePlus
- a602002
- Drug.DailyMedID
- Desloratadine
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- By mouth
- Drug.class
- Second-generation antihistamine
- Drug.ATC_prefix
~4 min read
Article
9 sectionsContents
- Medical uses
- Side effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Pharmacogenomics
- References
- Further reading
Desloratadine, sold under the brand name Aerius among others, is a tricyclic H1 inverse agonist that is used to treat allergies. It is the major active metabolite of loratadine.
It was patented in 1984 and came into medical use in 2001. It was brought to the market in the US by Schering Corporation, later named Schering-Plough.