isothipendyl
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Isothipendyl is a 1st generation H1 antagonist (antihistamine) and anticholinergic used as an antipruritic. In the 2020s, at least, it is rarely used in the first line relief of allergies due to the anticholinergic side effect of somnolence but does have some limited use through topical application in the relief of insect bites and related itching (pruritus).
Research
30 papers- Contact photoallergy to isothipendyl chlorhydrate.Dermatology (Basel, Switzerland) · 2012
- Phototoxic and photoprotective effects of topical isothipendyl.Photodermatology, photoimmunology & photomedicine · 1995
- Photodermatitis from topical phenothiazines: A case series.Contact dermatitis · 2020
- Contact allergy to isothipendyl.Contact dermatitis · 1983
- A clinical trial of isothipendyl hydrochloride (nilergex) in dermatology.Scottish medical journal · 1960
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 285.129969
- Has use
- medication
Show 4 more facts
- canonical SMILES
- CC(CN1C2=CC=CC=C2SC3=C1N=CC=C3)N(C)C
- chemical formula
- C₁₆H₁₉N₃S
- subject has role
- histamine antagonist
- Commons category
- Isothipendyl
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
2 sectionsContents
- See also
- References
Isothipendyl is a 1st generation H1 antagonist (antihistamine) and anticholinergic used as an antipruritic. In the 2020s, at least, it is rarely used in the first line relief of allergies due to the anticholinergic side effect of somnolence but does have some limited use through topical application in the relief of insect bites and related itching (pruritus).
== See also== Promethazine Prothipendyl
Excerpted from Wikipedia’s “isothipendyl” article, available under the CC BY-SA 4.0 licence.