dibucaine
Also known as Cincain ®, cincaine chloride, Nupercaine ®, CINCHOCAINE, 2-butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide, alpha-butyloxycinchoninic acid diethylethylenediamide, 2-butoxy-N-(beta-diethylaminoethyl)cinchoninamide
Cinchocaine (INN/BAN) or dibucaine (USAN) is an amide local anesthetic. Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia. It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine.
Chemical data
- Formula
- C20H29N3O2
- Molecular weight
- 343.5 g/mol
- IUPAC name
- 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
- SMILES
- CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC
- InChIKey
- PUFQVTATUTYEAL-UHFFFAOYSA-N
- XLogP
- 4.4
- Polar surface area
- 54.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
1,511 papers~1 min read
Article
5 sectionsContents
- Medical use
- Physical properties
- See also
- References
- Further reading
Cinchocaine (INN/BAN) or dibucaine (USAN) is an amide local anesthetic. Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia. It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine.
==Medical use== Cinchocaine is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle.