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clocinizine

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EntityQ5134770· pop 5· linked from 470 articles

clocinizine

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Clocinizine is a first-generation antihistamine of the diphenylmethylpiperazine class. It is marketed in Spain in combination with phenylpropanolamine under the brand name Senioral.

In the Vinony graph

Within Vinony's link graph, clocinizine is referenced by 470 other articles, and connects out to (RS)-meclizine, Spain and digital object identifier.

Vinony files it under Chemical pages without DrugBank identifier, Chlorcyclizines and Drugs not assigned an ATC code.

Its subject is documented across 4 Wikipedia language editions.

Chemical data

Formula
C26H27ClN2
Molecular weight
403 g/mol
IUPAC name
1-[(4-chlorophenyl)-phenylmethyl]-4-[(E)-3-phenylprop-2-enyl]piperazine
SMILES
C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl
InChIKey
ZSQANMZWGKYDER-JXMROGBWSA-N
XLogP
6.4
Polar surface area
6.5 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Mass
402.186
Show 4 more facts
chemical formula
C₂₆H₂₇ClN₂
canonical SMILES
C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl
isomeric SMILES
C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl
Commons category
Clocinizine
Sources (1)

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Encyclopedic overview

2 sections
Contents
  • Synthesis
  • References

Clocinizine is a first-generation antihistamine of the diphenylmethylpiperazine class. It is marketed in Spain in combination with phenylpropanolamine under the brand name Senioral.

==Synthesis== thumb|center|500px|class=skin-invert-image|Synthesis: Patent:

Excerpted from Wikipedia’s “clocinizine” article, available under the CC BY-SA 4.0 licence.

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