beraprost

Also known as MDL 201229, MDL-201229, ML 1229, ML-1229

Beraprost is a pharmaceutical drug used in several Asian countries, including Japan and South Korea, as a vasodilator and antiplatelet agent. It is classified as a prostacyclin analog.

Chemical data

Formula: C24H30O5
Molecular weight: 398.5 g/mol
IUPAC name: 4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoic acid

via PubChem

Research

575 papers

Beraprost: a review of its pharmacology and therapeutic efficacy in the treatment of peripheral arterial disease and pulmonary arterial hypertension.Drugs · 2002
Beraprost sodium ameliorates cognitive impairment by promoting oligodendrocyte precursor cell proliferation and differentiation in vascular cognitive impairment mouse model.Neuropharmacology · 2025
The effects of beraprost sodium on renal function and cardiometabolic profile in patients with diabetes mellitus: a systematic review and meta-analysis of clinical trials.International urology and nephrology · 2022
Beraprost and Overall Survival in Cats with Chronic Kidney Disease.Veterinary sciences · 2023
Beraprost ameliorates postmenopausal osteoporosis by regulating Nedd4-induced Runx2 ubiquitination.Cell death & disease · 2021

via PubMed

Wikidata facts

Mass: 398.209324

Show 2 more facts

chemical formula: C₂₄H₃₀O₅
canonical SMILES: CC#CCC(C)C(C=CC1C(CC2C1C3=C(O2)C(=CC=C3)CCCC(=O)O)O)O

Sources (1)

wikidata.org

via Wikidata · CC0

~2 min read

Article

3 sections

Contents

Clinical pharmacology
Dosage and administration
References

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