indoprofen

Also known as K-4277, 2-(4-(1-Carboxyethyl)phenyl)-1-isoindolinone, K 4277, alpha-(4-(1-Oxo-2-isoindolinyl)phenyl)propionic acid, 1-Oxo-2-(p-((alpha-methyl)carboxymethyl)phenyl)isoindoline

Indoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.

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Synthesis
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Indoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.

A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.