Structure via PubChem · Public domain (PubChem)
ethenzamide
Sign in to saveAlso known as 2-ethoxybenzamide
Ethenzamide (2-ethoxybenzamide) is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains. It is also an ingredient in numerous cold medications and many prescription analgesics. It is used as an over-the-counter drug in Japan, often in combination with caffeine and acetaminophen, where it is marketed for uses including toothache, menstrual cramps, headache, and fever.
In the Vinony graph
Within Vinony's link graph, ethenzamide is referenced by 501 other articles, and connects out to Paracetamol, salicylic acid and metamizole sodium.
It sits within the topics Benzamides, Chemical pages without DrugBank identifier and Drugs with no legal status.
Its subject is documented across 17 Wikipedia language editions.
Chemical data
- Formula
- C9H11NO2
- Molecular weight
- 165.19 g/mol
- IUPAC name
- 2-ethoxybenzamide
- SMILES
- CCOC1=CC=CC=C1C(=O)N
- InChIKey
- SBNKFTQSBPKMBZ-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 52.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- pain, Fever
via ChEMBL · EBI
Research
109 papers- Ethenzamide Exerts Analgesic Effect at the Spinal Cord via Multiple Mechanisms of Action Including the 5HT(2B) Receptor Blockade in the Rat Formalin Test.Biological & pharmaceutical bulletin · 2020
- Ethenzamide Exerts Protective Effects against Ibuprofen-Induced Gastric Mucosal Damage in Rats by Suppressing Gastric Contraction.Biological & pharmaceutical bulletin · 2021
- Investigation into polymorphism within ethenzamide-ethylmalonic acid cocrystal using Raman and terahertz vibrational spectroscopy.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2024
- Amorphization of Ethenzamide and Ethenzamide Cocrystals-A Case Study of Single and Binary Systems Forming Low-Melting Eutectic Phases Loaded on/in Silica Gel.Pharmaceutics · 2023
- Pharmaceutical Cocrystals of Ethenzamide: Molecular Structure Analysis Based on Vibrational Spectra and DFT Calculations.International journal of molecular sciences · 2022
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 165.079
Show 5 more facts
- chemical formula
- C₉H₁₁NO₂
- canonical SMILES
- CCOC1=CC=CC=C1C(=O)N
- subject has role
- non-steroidal anti-inflammatory drug
- melting point
- 133
- Commons category
- 2-Ethoxybenzamide
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Ethenzamide (2-ethoxybenzamide) is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains. It is also an ingredient in numerous cold medications and many prescription analgesics. It is used as an over-the-counter drug in Japan, often in combination with caffeine and acetaminophen, where it is marketed for uses including toothache, menstrual cramps, headache, and fever.
It is metabolized in vivo into salicylamide.
Excerpted from Wikipedia’s “ethenzamide” article, available under the CC BY-SA 4.0 licence.