Structure via PubChem · Public domain (PubChem)
MDAT
Sign in to saveAlso known as 6,7-methylenedioxy-2-aminotetralin
MDAT, also known as 6,7-methylenedioxy-2-aminotetralin, is a drug of the 2-aminotetralin family developed in the 1990s by a team at Purdue University led by David E. Nichols. It appears to act as a serotonin releasing agent based on rodent drug discrimination assays comparing it to MDMA, in which it fully substitutes for, and additionally lacks any kind of serotonergic neurotoxicity. Hence, MDAT is considered likely to be a non-neurotoxic, putative entactogen in humans.
Chemical data
- Formula
- C11H13NO2
- Molecular weight
- 191.23 g/mol
- IUPAC name
- 5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxol-6-amine
- SMILES
- C1CC2=CC3=C(C=C2CC1N)OCO3
- InChIKey
- AWSBQWZZLBPUQH-UHFFFAOYSA-N
- XLogP
- 1.5
- Polar surface area
- 44.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 191.094629
Show 2 more facts
- chemical formula
- C₁₁H₁₃NO₂
- canonical SMILES
- C1CC2=CC3=C(C=C2CC1N)OCO3
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
MDAT, also known as 6,7-methylenedioxy-2-aminotetralin, is a drug of the 2-aminotetralin family developed in the 1990s by a team at Purdue University led by David E. Nichols. It appears to act as a serotonin releasing agent based on rodent drug discrimination assays comparing it to MDMA, in which it fully substitutes for, and additionally lacks any kind of serotonergic neurotoxicity. Hence, MDAT is considered likely to be a non-neurotoxic, putative entactogen in humans.
==See also== Substituted 2-aminotetralin Substituted methylenedioxyphenethylamine Cyclized phenethylamine
Excerpted from Wikipedia’s “MDAT” article, available under the CC BY-SA 4.0 licence.