methylarginine
Sign in to saveAlso known as N-methyl-DL-arginine
'''N-Methylarginine''' is an inhibitor of nitric oxide synthase. Chemically, it is a methyl derivative of the amino acid arginine. It is used as a biochemical tool in the study of physiological role of nitric oxide.
Wikidata facts
- Subclass of
- amino acid
- Mass
- 188.127326
Show 4 more facts
- chemical formula
- C₇H₁₆N₄O₂
- isomeric SMILES
- C/N=C(\N)/NCCCC(C(=O)O)N
- canonical SMILES
- CN=C(N)NCCCC(C(=O)O)N
- found in taxon
- broad bean
Sources (2)
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Encyclopedic overview
2 sectionsContents
- See also
- References
'''N-Methylarginine' is an inhibitor of nitric oxide synthase. Chemically, it is a methyl derivative of the amino acid arginine. It is used as a biochemical tool in the study of physiological role of nitric oxide.
The inhibiting effect of N-methylarginine on vasodilation is lower in hypertensive patients than in normal subjects, indicating endothelial dysfunction. The inhibiting effect of N''-methylarginine on vasodilation declines progressively with age, but has been restored with vitamin C in the oldest subjects.
Excerpted from Wikipedia’s “methylarginine” article, available under the CC BY-SA 4.0 licence.