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methylarginine

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Also known as N-methyl-DL-arginine

'''N-Methylarginine''' is an inhibitor of nitric oxide synthase. Chemically, it is a methyl derivative of the amino acid arginine. It is used as a biochemical tool in the study of physiological role of nitric oxide.

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'''N-Methylarginine' is an inhibitor of nitric oxide synthase. Chemically, it is a methyl derivative of the amino acid arginine. It is used as a biochemical tool in the study of physiological role of nitric oxide.

The inhibiting effect of N-methylarginine on vasodilation is lower in hypertensive patients than in normal subjects, indicating endothelial dysfunction. The inhibiting effect of N''-methylarginine on vasodilation declines progressively with age, but has been restored with vitamin C in the oldest subjects.

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