microdosing
Sign in to saveAlso known as micro-dosing
Microdosing, or micro-dosing, involves the administration of sub-therapeutic doses of drugs to study their effects in humans, aiming to gather preliminary data on safety, pharmacokinetics, and potential therapeutic benefits without producing significant physiological effects. This is called a "Phase 0 study" and is usually conducted before clinical Phase I to predict whether a drug is viable for the next phase of testing. Human microdosing aims to reduce the resources spent on non-viable drugs and the amount of testing done on animals.
~7 min read
Article
7 sectionsContents
- Techniques
- Psychedelic
- Impact of psychedelic microdosing
- See also
- References
- Further reading
- External links
Microdosing, or micro-dosing, involves the administration of sub-therapeutic doses of drugs to study their effects in humans, aiming to gather preliminary data on safety, pharmacokinetics, and potential therapeutic benefits without producing significant physiological effects. This is called a "Phase 0 study" and is usually conducted before clinical Phase I to predict whether a drug is viable for the next phase of testing. Human microdosing aims to reduce the resources spent on non-viable drugs and the amount of testing done on animals.
Less commonly, the term "microdosing" can be used to refer to precise dispensing of small amounts of a drug substance (, a powder API) for a drug product (, a capsule) and, when the drug substance also happens to be liquid, this can potentially overlap with the term microdispensing .