MLLT10

Also known as AF10, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10, MLLT10, histone lysine methyltransferase DOT1L cofactor, MLLT10 histone lysine methyltransferase DOT1L cofactor

Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene.

Gene data

MLLT10

Name: MLLT10 histone lysine methyltransferase DOT1L cofactor
Type: protein-coding
Position: 21,524,617–21,743,630 (+)
Aliases: AF10
Ensembl: ENSG00000078403
RefSeq RNA: NM_001009569.1, NM_001195626.3, NM_001195627.2, NM_001195628.2, NM_001195630.2
RefSeq protein: NP_001182555.1, NP_001182556.1, NP_001182557.1, NP_001182559.1, NP_001311225.1

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010].