Structure via PubChem · Public domain (PubChem)
Morpheridine
Sign in to saveMorpheridine (Morpholinoethylnorpethidine) is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine). It is a strong analgesic with around 4 times the potency of pethidine, and unlike pethidine, does not cause convulsions, although it produces the standard opioid side effects such as sedation and respiratory depression.
Chemical data
- Formula
- C20H30N2O3
- Molecular weight
- 346.5 g/mol
- IUPAC name
- ethyl 1-(2-morpholin-4-ylethyl)-4-phenylpiperidine-4-carboxylate
- SMILES
- CCOC(=O)C1(CCN(CC1)CCN2CCOCC2)C3=CC=CC=C3
- InChIKey
- JDEDMCKQPKGSAX-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 42 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 346.226
Show 3 more facts
- chemical formula
- C₂₀H₃₀N₂O₃
- canonical SMILES
- CCOC(=O)C1(CCN(CC1)CCN2CCOCC2)C3=CC=CC=C3
- Commons category
- Morpheridine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Morpheridine (Morpholinoethylnorpethidine) is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine). It is a strong analgesic with around 4 times the potency of pethidine, and unlike pethidine, does not cause convulsions, although it produces the standard opioid side effects such as sedation and respiratory depression.
Morpheridine is not currently used in medicine and is a Schedule I drug which is controlled under UN drug conventions.
Excerpted from Wikipedia’s “Morpheridine” article, available under the CC BY-SA 4.0 licence.