motor neuron
Sign in to saveAlso known as motoneuron, efferent neuron, motor neurons
neuron with cell body in the motor cortex, brainstem or the spinal cord, and axon controlling effector organs, mainly muscles and glands
Key facts
- Location
- Ventral horn of the spinal cord , some cranial nerve nuclei
- Shape
- Projection neuron
- Function
- Excitatory projection (to [
- Neurotransmitter
- UMN to LMN : glutamate ; LMN to NMJ : ACh
- Presynaptic connections
- Primary motor cortex via the Corticospinal tract
- Postsynaptic connections
- Muscle fibers and other neurons
- Mesh
- D009046
- Neurolex id
- nifext_103
- Ta98
- A14.2.00.021
via Wikipedia infobox
Research
114,125 papers- Autophagy and Motor Neuron Diseases.Advances in experimental medicine and biology · 2020
- Astrocytes in Motor Neuron Diseases.Advances in experimental medicine and biology · 2019
- Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.Science (New York, N.Y.) · 1994
- Cytoskeleton dysfunction of motor neuron in spinal muscular atrophy.Journal of neurology · 2024
- Motor neuron migration and positioning mechanisms: New roles for guidance cues.Seminars in cell & developmental biology · 2019
via PubMed
~15 min read
Encyclopedic overview
A motor neuron (or motoneuron), also known as efferent neuron is a neuron that allows for both voluntary and involuntary movements of the body through muscles and glands. Its cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. There are two types of motor neuron – upper motor neurons and lower motor neurons. Axons from upper motor neurons synapse onto interneurons in the spinal cord and occasionally directly onto lower motor neurons. The axons from the lower motor neurons are efferent nerve fibers that carry signals from the spinal cord to the effectors. Types of lower motor neurons are alpha motor neurons, beta motor neurons, and gamma motor neurons.
A single motor neuron may innervate many muscle fibres and a muscle fibre can undergo many action potentials in the time taken for a single muscle twitch. Innervation takes place at a neuromuscular junction and twitches can become superimposed as a result of summation or a tetanic contraction. Individual twitches can become indistinguishable, and tension rises smoothly eventually reaching a plateau.
Excerpted from Wikipedia’s “motor neuron” article, available under the CC BY-SA 4.0 licence.