File:Multiple_myeloma_(1)_MG_stain.jpg · Wikimedia Commons · See Wikimedia Commons
Multiple myeloma is a cancer that develops in plasma cells, which are a type of white blood cell found in bone marrow. It matters because it can damage bones, interfere with the production of healthy blood cells, and affect kidney function, making it a serious condition that requires medical treatment.
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Research
71,283 papers- Pathobiology and Diagnosis of Multiple Myeloma.ReviewSeminars in oncology nursing · 2017Brigle K, Rogers BDOI: 10.1016/j.soncn.2017.05.012
- Multiple myeloma.ReviewThe New England journal of medicine · 2011Palumbo A, Anderson KDOI: 10.1056/NEJMra1011442
- Haematology: multiple myeloma.ReviewClinical medicine (London, England) · 2019Medical Masterclass contributors, Firth JDOI: 10.7861/clinmedicine.19-1-58
- Multiple myeloma: Every year a new standard?ReviewHematological oncology · 2019Rajkumar SVDOI: 10.1002/hon.2586
- Multiple myeloma.ReviewSeminars in oncology nursing · 1996Sheridan CADOI: 10.1016/s0749-2081(96)80019-2
- Multiple myeloma.ReviewCritical reviews in oncology/hematology · 1998Zulian GB, Babare R, Zagonel VDOI: 10.1016/s1040-8428(97)10030-0
- Extramedullary Multiple Myeloma.ReviewEuropean journal of haematology · 2026Jingliang Z, Xiaoqi QDOI: 10.1111/ejh.70145
- Multiple myeloma.ReviewRadiologic technology · 2005White TB, Caldwell D, Hall-Rollins J
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Wikidata facts
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- Multiple Myeloma.jpg
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- Commons category
- Multiple myeloma
- NCI Thesaurus ID
- C3242
- exact match
- identifiers.org/doid/DOID:9538
- ICD-9-CM
- 203.0
Sources (9)
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Article
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. Complications may include hypercalcemia and amyloidosis.
The cause of multiple myeloma is unknown. Risk factors include obesity, radiation exposure, family history, age and certain chemicals. There is an increased risk of multiple myeloma in certain occupations, due to occupational exposure to aromatic hydrocarbon solvents. Multiple myeloma is the result of a multi-step malignant transformation, and almost universally originates from the pre-malignant stage monoclonal gammopathy of undetermined significance (MGUS). As MGUS evolves into MM, another pre-stage of the disease is reached, known as smoldering myeloma (SMM).