nitrogenase
Sign in to saveAlso known as reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing), nitrogenases
Nitrogenases are enzymes () that are produced by certain bacteria, such as cyanobacteria (blue-green bacteria) and rhizobacteria. These enzymes are responsible for the reduction of nitrogen (N2) to ammonia (NH3). Nitrogenases are the only family of enzymes known to catalyze this reaction, which is a step in the process of nitrogen fixation. Nitrogen fixation is required for all forms of life, with nitrogen being essential for the biosynthesis of molecules (nucleotides, amino acids) that create plants, animals and other organisms. They are encoded by the Nif genes or homologs. They are related
Key facts
- Enzyme.Name
- Nitrogenase
- Enzyme.EC_number
- 1.18.6.1
- Enzyme.CAS_number
- 9013-04-1
- Enzyme.image
- Nitrogenase.png
- Protein family.Name
- Alternative nitrogenase (component 1) delta subunit
- Protein family.Pfam
- PF03139
- Protein family.Symbol
- AnfG_VnfG
- Protein family.InterPro
- IPR004349
- Protein family.SCOP
- d1fp6a_
- Protein family.CDD
- cd02040
- Protein family.CATH
- 1fp6
via Wikipedia infobox
Research
6,165 papers- Nitrogenase Bioelectrochemistry for Synthesis Applications.Accounts of chemical research · 2019
- Nitrogenase and homologs.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2015
- Electron Transfer in Nitrogenase.Chemical reviews · 2020
- Nitrogenase beyond the Resting State: A Structural Perspective.Molecules (Basel, Switzerland) · 2023
- Nitrogenase.Nature · 1974
via PubMed
Wikidata facts
- Image
- The FeMo cofactor of nitrogenase, ((R-homocitrate)MoFe7S9C).png
Show 2 more facts
- EC enzyme number
- 1.18.6.1
- Commons category
- Nitrogenase
Sources (2)
via Wikidata · CC0
~26 min read
Article
21 sectionsContents
- Classification and structure
- Reductase
- Nitrogenase
- Variations
- Mechanism
- General mechanism
- Lowe-Thorneley kinetic model
- Intermediates E<sub>0</sub> through E<sub>4</sub>
- Distal and alternating pathways for N<sub>2</sub> fixation
- Mechanism of MgATP binding
- Other mechanistic details
- Nonspecific reactions
- Organisms that synthesize nitrogenase
- Evolution
- Internal evolution
- Similarity to other proteins
- Measurement of nitrogenase activity
- See also
- References
- Further reading
- External links
Nitrogenases are enzymes () that are produced by certain bacteria, such as cyanobacteria (blue-green bacteria) and rhizobacteria. These enzymes are responsible for the reduction of nitrogen (N2) to ammonia (NH3). Nitrogenases are the only family of enzymes known to catalyze this reaction, which is a step in the process of nitrogen fixation. Nitrogen fixation is required for all forms of life, with nitrogen being essential for the biosynthesis of molecules (nucleotides, amino acids) that create plants, animals and other organisms. They are encoded by the Nif genes or homologs. They are related to protochlorophyllide reductase.
==Classification and structure==