NME8
Sign in to saveAlso known as CILD6, NM23-H8, SPTRX2, TXNDC3, sptrx-2, HEL-S-99, NME/NM23 family member 8, DNAI8
Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7.
In the Vinony graph
Vinony's link graph records 62 inbound references to NME8, and connects out to Q180686, human chromosome 7 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 7.
Vinony links it to 5 Wikipedia language editions.
Gene data
NME8- Name
- NME/NM23 family member 8
- Type
- protein-coding
- Aliases
- CILD6, DNAI8, HEL-S-99, NDK8, NM23-H8, SPTRX2, TXNDC3, sptrx-2
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009].
via MyGene.info
Gene · Ensembl
NME/NM23 family member 8
- Symbol
- NME8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:37,848,597-37,900,397
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9593
- exact match
- identifiers.org/ncbigene/51314
- genomic end
- 37900397
- genomic start
- 37888199
- cytogenetic location
- 7p14.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- References
- Further reading
- External links
Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7.
== Function ==
Excerpted from Wikipedia’s “NME8” article, available under the CC BY-SA 4.0 licence.