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GeneQ18040206· pop 5· linked from 62 articles

Also known as CILD6, NM23-H8, SPTRX2, TXNDC3, sptrx-2, HEL-S-99, NME/NM23 family member 8, DNAI8

Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7.

In the Vinony graph

Vinony's link graph records 62 inbound references to NME8, and connects out to Q180686, human chromosome 7 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 7.

Vinony links it to 5 Wikipedia language editions.

Gene data

NME8
Name
NME/NM23 family member 8
Type
protein-coding
Aliases
CILD6, DNAI8, HEL-S-99, NDK8, NM23-H8, SPTRX2, TXNDC3, sptrx-2

This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009].

via MyGene.info

Gene · Ensembl

NME/NM23 family member 8

Symbol
NME8
Biotype
Protein coding
Organism
Homo sapiens
Location
7:37,848,597-37,900,397
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
9593
genomic end
37900397
genomic start
37888199
cytogenetic location
7p14.1
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Function
  • Clinical significance
  • References
  • Further reading
  • External links

Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7.

== Function ==

Excerpted from Wikipedia’s “NME8” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

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