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EntityQ4327388· pop 10· linked from 17 articles

norcodeine (stereochemistry defined)

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Also known as N-Norcodeine, N-demethylcodeine

Norcodeine is an opiate analogue that is the N-demethylated derivative of codeine. It has relatively little opioid activity in its own right, but is formed as a metabolite of codeine following ingestion.

Wikidata facts

Mass
285.136493
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chemical formula
C₁₇H₁₉NO₃
canonical SMILES
COC1=C2C3=C(CC4C5C3(CCN4)C(O2)C(C=C5)O)C=C1
isomeric SMILES
[C@@]123C4=C5C(=CC=C4C[C@H]([C@@]1(C=C[C@@H]([C@@H]2O5)O)[H])NCC3)OC
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Norcodeine is an opiate analogue that is the N-demethylated derivative of codeine. It has relatively little opioid activity in its own right, but is formed as a metabolite of codeine following ingestion.

Norcodeine is a Schedule I Narcotic controlled substance in the US with the ACSCN of 9309 and zero annual manufacturing quota. The salts in use are the acetate (free base conversion ratio 0.826), hydroiodide (0.662), hydrochloride (0.759), nitrate (0.819), platinichloride (0.582), and sulphate (0.744).

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