NOX5
Sign in to saveAlso known as NADPH oxidase 5
NADPH oxidase, EF-hand calcium binding domain 5, also known as NOX5, is a protein which in humans is encoded by the NOX5 gene.
Gene data
NOX5- Name
- NADPH oxidase 5
- Type
- protein-coding
- Position
- 69,014,690–69,062,762 (+)
- Ensembl
- ENSG00000255346
- RefSeq RNA
- NM_001184779.2, NM_024505.4
- RefSeq protein
- NP_001171708.1, NP_078781.3
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
NADPH oxidase 5
- Symbol
- NOX5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:69,014,690-69,062,762
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 41568
- genetic association
- obesity
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/79400
- genomic end
- 69062762
- genomic start
- 69222864
- chromosome
- human chromosome 15
- cytogenetic location
- 15q23
- expressed in
- placenta
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
NADPH oxidase, EF-hand calcium binding domain 5, also known as NOX5, is a protein which in humans is encoded by the NOX5 gene.
== Function ==
Excerpted from Wikipedia’s “NOX5” article, available under the CC BY-SA 4.0 licence.