NSRP1

Also known as CCDC55, HSPC095, NSrp70, nuclear speckle splicing regulatory protein 1

Nuclear speckle splicing regulatory protein 1 is a protein that in humans is encoded by the NSRP1 gene.

Gene data

NSRP1

Name: nuclear speckle splicing regulatory protein 1
Type: protein-coding
Position: 30,115,521–30,186,475 (+)
Aliases: CCDC55, HSPC095, NEDSSBA, NSrp70
Ensembl: ENSG00000126653
RefSeq RNA: NM_001033563.1, NM_001261467.2, NM_032141.4, XM_011525345.3, XM_047436916.1
RefSeq protein: NP_001248396.1, NP_115517.1, XP_011523647.1, XP_047292872.1, XP_047292873.1

Enables mRNA binding activity. Involved in developmental process and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome

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Article

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Further reading

Nuclear speckle splicing regulatory protein 1 is a protein that in humans is encoded by the NSRP1 gene.

NSRP1 is located within nuclear speckles. Speckles are dynamic membrane-less organelles within the nucleus and are rich in RNA splicing factors. NSRP1 interacts with other splicing factors including SRSF1 and SRSF2 and modulates pre-mRNA splicing. Knockout of the mouse ortholog Nsrp1 resulted in early embryonic lethality.