nucleic acid sequence
Sign in to saveAlso known as base sequence, nucleotide sequence
succession of letters that indicate the order of nucleotides within a DNA (using GACT) or RNA (GACU) molecule
Research
826,756 papers- Guidelines for Sanger sequencing and molecular assay monitoring.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
- Nucleic acid sequence analysis software packages.Current opinion in biotechnology · 1994
- An extra dimension in nucleic acid sequence recognition.Quarterly reviews of biophysics · 2005
- Nucleic acid sequence database VI: Retroviral oncogenes and cellular proto-oncogenes.DNA (Mary Ann Liebert, Inc.) · 1985
- Nucleic acid sequence-based amplification.Nature · 1991
via PubMed
Wikidata facts
- Image
- DNA RNA structure (1).png
Show 2 more facts
- Commons category
- Nucleic acid sequence
- NCI Thesaurus ID
- C45374
Sources (3)
via Wikidata · CC0
~13 min read
Article
The image above contains clickable links Interactive image of nucleic acid structure (primary, secondary, tertiary, and quaternary) using DNA helices and examples from the VS ribozyme and telomerase and nucleosome. (PDB: ADNA, 1BNA, 4OCB, 4R4V, 1YMO, 1EQZ)
A nucleic acid sequence is a succession of bases within the nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule. This succession is denoted by a series of a set of five different letters that indicate the order of the nucleotides. By convention, sequences are usually presented from the 5' end to the 3' end. For DNA, with its double helix, there are two possible directions for the notated sequence; of these two, the sense strand is used. Because nucleic acids are normally linear (unbranched) polymers, specifying the sequence is equivalent to defining the covalent structure of the entire molecule. For this reason, the nucleic acid sequence is also termed the primary structure.