NUDT3
Sign in to saveAlso known as DIPP, DIPP-1, DIPP1, nudix hydrolase 3
Diphosphoinositol polyphosphate phosphohydrolase 1 is an enzyme that in humans is encoded by the NUDT3 gene.
Gene data
NUDT3- Name
- nudix hydrolase 3
- Type
- protein-coding
- Position
- 34,263,257–34,392,832 (−)
- Aliases
- DIPP, DIPP-1, DIPP1
- Ensembl
- ENSG00000272325
- RefSeq RNA
- NM_006703.4
- RefSeq protein
- NP_006694.1
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]).[supplied by OMIM, Feb 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
nudix hydrolase 3
- Symbol
- NUDT3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:34,263,257-34,392,832
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Diphosphoinositol polyphosphate phosphohydrolase 1 is an enzyme that in humans is encoded by the NUDT3 gene.
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998).[supplied by OMIM]
Excerpted from Wikipedia’s “NUDT3” article, available under the CC BY-SA 4.0 licence.