OPTC
Sign in to saveAlso known as OPT, opticin
Opticin is a protein that in humans is encoded by the OPTC gene.
Gene data
OPTC- Name
- opticin
- Type
- protein-coding
- Aliases
- OPT
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
opticin
- Symbol
- OPTC
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:203,494,118-203,509,238
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8652
- exact match
- identifiers.org/ncbigene/26254
- genomic end
- 203508949
- genomic start
- 203494153
- cytogenetic location
- 1q32.1
Sources (3)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Opticin is a protein that in humans is encoded by the OPTC gene.
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).