ormeloxifene
Sign in to saveAlso known as centchroman
Ormeloxifene, also known as centchroman, is one of the selective estrogen receptor modulators, or SERMs, a class of medication which acts on the estrogen receptor. It is best known as a nonsteroidal oral contraceptive which is taken once per week. In India, ormeloxifene has been available as birth control since the early 1990s, and it was marketed there under the trade name Saheli, currently available free-of-cost for the women in India as Chhaya (Centchroman).
Key facts
- Birth control.bc_type
- Antiestrogen
- Birth control.date_first_use
- 1991
- Birth control.rate_type
- Failure
- Birth control.perfect_failure%
- 2
- Birth control.typical_failure%
- 9
- Birth control.duration_effect
- One week
- Birth control.reversibility
- Immediate
- Birth control.user_reminders
- Taken twice weekly for first 13 weeks
- Birth control.clinic_interval
- Annually
- Birth control.STD_protection_YesNo
- No
- Birth control.benefits
- Non hormonal
- Birth control.breastfeeding_YesNo
- Yes
- Birth control.periods
- May disrupt
- Birth control.weight_gain_loss
- No proven effect
- Birth control.risks
- Delayed menstruation
- Birth control.medical_notes
- Only approved as a contraceptive in India
via Wikipedia infobox
Research
223 papers- Ormeloxifene Versus Norethisterone for Anovulatory Abnormal Uterine Bleeding: An India-Based Systematic Review and Meta-Analysis.Cureus · 2025
- Ormeloxifene, a selective estrogen receptor modulator, protects against pulmonary hypertension.European journal of pharmacology · 2023
- Ormeloxifene nanotherapy for cervical cancer treatment.International journal of nanomedicine · 2019
- Ormeloxifene, a nonsteroidal antifertility drug promotes megakaryocyte differentiation in leukemia cell line K562.Cell biology international · 2023
- Ormeloxifene Suppresses Prostate Tumor Growth and Metastatic Phenotypes via Inhibition of Oncogenic β-catenin Signaling and EMT Progression.Molecular cancer therapeutics · 2017
via PubMed
Wikidata facts
- Mass
- 457.261694
Show 4 more facts
- chemical formula
- C₃₀H₃₅NO₃
- canonical SMILES
- CC1(C(C(C2=C(O1)C=C(C=C2)OC)C3=CC=C(C=C3)OCCN4CCCC4)C5=CC=CC=C5)C
- isomeric SMILES
- CC1([C@@H]([C@H](C2=C(O1)C=C(C=C2)OC)C3=CC=C(C=C3)OCCN4CCCC4)C5=CC=CC=C5)C
- Commons category
- Ormeloxifene
Sources (1)
via Wikidata · CC0
~4 min read
Article
12 sectionsContents
- Medical uses
- Birth control
- Other indications
- Side effects
- Pharmacology
- History
- Society and culture
- Marketing
- See also
- References
- Further reading
- External links
Ormeloxifene, also known as centchroman, is one of the selective estrogen receptor modulators, or SERMs, a class of medication which acts on the estrogen receptor. It is best known as a nonsteroidal oral contraceptive which is taken once per week. In India, ormeloxifene has been available as birth control since the early 1990s, and it was marketed there under the trade name Saheli, currently available free-of-cost for the women in India as Chhaya (Centchroman).
Ormeloxifene has also been licensed under the trade names Ormalin, Novex-DS, Centron, and Sevista.
Available in 9 languages
via Wikidata sitelinks · CC0