Structure via PubChem · Public domain (PubChem)
palmatine
Sign in to saveAlso known as berbericinine, 7,8,13,13a-tetrahydro-2,3,9,10-tetramethoxyberbinium, O,O-dimethyldemethyleneberberine, 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium, 5,6-Dihydro-2,3,9,10-tetramethoxy-dibenzo[a,g]quinolizinium, Burasaine, Calystigine
Palmatine is a protoberberine alkaloid found in several plants including Coptis chinensis (Rhizoma coptidis, chinese goldthread), Corydalis yanhusuo, Tinospora cordifolia (gurjo, heart-leaved moonseed), Tinospora sagittata, Phellodendron amurense (amur cork tree), and Stephania yunnanensis.
Chemical data
- Formula
- C21H22NO4+
- Molecular weight
- 352.4 g/mol
- IUPAC name
- 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
- SMILES
- COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC
- InChIKey
- QUCQEUCGKKTEBI-UHFFFAOYSA-N
- XLogP
- 3.7
- Polar surface area
- 40.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 1
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- quaternary ammonium cation
- Mass
- 352.154883
Show 4 more facts
- chemical formula
- C₂₁H₂₂NO₄⁺
- found in taxon
- Tinospora sagittata
- canonical SMILES
- COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC
- Commons category
- Palmatine
via Wikidata · CC0
~4 min read
Encyclopedic overview
11 sectionsContents
- Biosynthesis
- Pharmacology
- Neuroprotective activity
- Regulating blood lipid activity
- Anticancer activity
- Antibacterial and antiviral activity
- Anti-inflammatory activity
- Other pharmacological activity
- Toxicity
- See also
- References
Palmatine is a protoberberine alkaloid found in several plants including Coptis chinensis (Rhizoma coptidis, chinese goldthread), Corydalis yanhusuo, Tinospora cordifolia (gurjo, heart-leaved moonseed), Tinospora sagittata, Phellodendron amurense (amur cork tree), and Stephania yunnanensis.
It is the major component of the protoberberine extract from Enantia chlorantha.
Excerpted from Wikipedia’s “palmatine” article, available under the CC BY-SA 4.0 licence.