PAPSS2
Sign in to saveAlso known as ATPSK2, BCYM4, SK2, 3'-phosphoadenosine 5'-phosphosulfate synthase 2
'''Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2' is an enzyme that in humans is encoded by the PAPSS2'' gene.
Gene data
PAPSS2- Name
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- Type
- protein-coding
- Aliases
- ATPSK2, BCYM4, SK2
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
3'-phosphoadenosine 5'-phosphosulfate synthase 2
- Symbol
- PAPSS2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:87,659,613-87,747,708
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein PAPSS2 PDB 2ax4.png
Show 5 more facts
- HomoloGene ID
- 55840
- exact match
- identifiers.org/ncbigene/9060
- genomic end
- 89507462
- genomic start
- 89419370
- cytogenetic location
- 10q23.2-q23.31
via Wikidata · CC0
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'''Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2' is an enzyme that in humans is encoded by the PAPSS2'' gene.
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.