PEF1
Sign in to saveAlso known as ABP32, PEF1A, penta-EF-hand domain containing 1
Peflin is a protein that in humans is encoded by the PEF1 gene.
Gene data
PEF1- Name
- penta-EF-hand domain containing 1
- Type
- protein-coding
- Position
- 31,629,862–31,644,910 (−)
- Aliases
- ABP32, PEF1A
- Ensembl
- ENSG00000162517
- RefSeq RNA
- NM_001359651.2, NM_012392.4, NR_033686.2, XM_011541745.2, XM_011541746.3
- RefSeq protein
- NP_001346580.1, NP_036524.1, XP_011540047.1, XP_011540048.1, XP_011540049.1
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
penta-EF-hand domain containing 1
- Symbol
- PEF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:31,629,862-31,644,910
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 56569
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/553115
- genomic end
- 32110497
- genomic start
- 31629866
- expressed in
- left coronary artery
- chromosome
- human chromosome 1
- cytogenetic location
- 1p35.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Peflin is a protein that in humans is encoded by the PEF1 gene.
PEF1 is a Ca(2+)-binding protein that belongs to the penta-EF hand (PEF) protein family, which includes the calpain small subunit (CAPNS1; MIM 114170), sorcin (SRI; MIM 182520), grancalcin (GCA; MIM 607030), and ALG2 (PDCD6; MIM 601057) (Kitaura et al., 2001).[supplied by OMIM]
Excerpted from Wikipedia’s “PEF1” article, available under the CC BY-SA 4.0 licence.