Gene data
PFDN1- Name
- prefoldin subunit 1
- Type
- protein-coding
- Position
- 140,234,986–140,303,119 (−)
- Aliases
- PDF, PFD1
- Ensembl
- ENSG00000113068
- RefSeq RNA
- NM_002622.5, XM_005268465.5, XM_054352822.1
- RefSeq protein
- NP_002613.2, XP_005268522.1, XP_054208797.1
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
prefoldin subunit 1
- Symbol
- PFDN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:140,234,986-140,303,119
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5201
- HomoloGene ID
- 37644
- genomic end
- 140303113
- genomic start
- 140245035
- chromosome
- human chromosome 5
- cytogenetic location
- 5q31.3
Sources (4)
via Wikidata · CC0
Article · Español
La subunidad 1 de prefoldina es una proteína que en los humanos está codificada por el gen PFDN1 . Este gen codifica un miembro de la familia de subunidades beta de prefoldina. La proteína codificada es una de las seis subunidades de prefoldina, un complejo de chaperona molecular que se une y estabiliza los polipéptidos recién sintetizados, lo que les permite plegarse correctamente. El complejo, que consta de dos subunidades alfa y cuatro beta, forma un conjunto de doble barril beta con seis bobinas en espiral que sobresalen.
Abstract from DBpedia / Wikipedia · CC BY-SA