PGA5

Name

pepsinogen A5

Type

protein-coding

Aliases

Pg5

This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015].

via MyGene.info

Gene · Ensembl

pepsinogen A5

Symbol

PGA5

Biotype

Protein coding

Organism

Homo sapiens

Location

11:61,241,175-61,251,444

Strand

Forward (+)

Assembly

GRCh38