File:Phillip_Sharp_HD2007_with_Winthrop_Sears_Medal.jpg · Wikimedia Commons · See Wikimedia Commons
Person · Open Library
- Works
- 1
Top works
- Glaciers in the Arctic
via Open Library + Wikidata
Music · MusicBrainz
- Type
- Person
- Gender
- Male
- Origin
- United States
- Active from
- 1951-03-01
Discography
- Nots1982
- (T)here1983
- Carbon1984
- Fractal1986
- Virtual Stance1986
- In the Land of the Yahoos1987
- Tessalation Row1987
- In New York1990
- K!L!A!V!1990
- Twistmap1991
via MusicBrainz · CC0
Recent publications · Crossref
5 total works indexed
- Unpaired Image-to-Image Translation Using Cycle-Consistent Adversarial Networks
· 2017 · cited 16,636x
- The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis
· 1988 · cited 15,767x
- Image-to-Image Translation with Conditional Adversarial Networks
· 2017 · cited 15,405x
- The Unreasonable Effectiveness of Deep Features as a Perceptual Metric
· 2018 · cited 11,707x
- Mussel-Inspired Surface Chemistry for Multifunctional Coatings
· 2007 · cited 10,322x
via Crossref · CC0
Key facts
- Born
- ( 1944-06-06 ) June 6, 1944 (age 81) , Falmouth, Kentucky , U.S.
- Education
- Union Commonwealth University ( BA ) University of Illinois at Urbana–Champaign ( PhD )
- Spouse
- Ann Holcombe ( married</span>"}]]}'>m. 1964 )
- Awards
- NAS Award in Molecular Biology (1980) Louisa Gross Horwitz Prize (1988) Dickson Prize (1991) Nobel Prize (1993) Novartis-Drew Award (2003) National Medal of Science (2004)
- Fields
- Biologist
- Institutions
- Caltech Cold Spring Harbor Laboratory MIT
- Doctoral students
- Connie Cepko Andrew Fire Melissa J. Moore Richard Carthew
- Website
- web .mit .edu /sharplab
via Wikipedia infobox
Wikidata facts
- Image
- Phillip Sharp HD2007 with Winthrop Sears Medal (cropped).jpg
Show 4 more facts
- Commons category
- Phillip Allen Sharp
- date of birth
- 1944-06-06
- Erdős number
- 5
- affiliation string
- Massachusetts Institute of Technology (MIT)
via Wikidata · CC0
~10 min read
Article
Phillip Allen Sharp (born June 6, 1944) is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for "the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence". He was awarded the 2015 Othmer Gold Medal.
Sharp's current research focuses on small RNAs and other types of non-coding RNAs. His laboratory works to identify the target mRNAs of microRNAs (miRNAs), and has discovered a class of miRNAs that are produced from sequences adjacent to transcription start sites. His laboratory also studies how miRNA gene regulation functions in angiogenesis and cellular stress.